Polarographic Determination of Isonicotinic Acid Hydrazide (INH) in Serum

Isonicotinic Acid Hydrazide

Isonicotinic Acid Hydrazide (inh) Conversion to Isonicotinyl-nad by Catalase-peroxidases*

CATALASE-PEROXIDASES* Ben Wiseman, Xavier Carpena, Miguel Feliz, Lynda J. Donald, Miquel Pons, Ignacio Fita and Peter C. Loewen From Departments of Microbiology and Chemistry, University of Manitoba, Winnipeg, MB R3T 2N2; Institute for Research in Biomedicine (IRB-Barcelona), and Institut de Biologia Molecular (IBMBCSIC), Parc Científic, Baldiri Reixac 10, 08028 Barcelona, Spain, and University...

Isonicotinic Acid Hydrazide in the Treatment of Lupus Vulgaris

Synthesis, antitubercular activity and pharmacokinetic studies of some Schiff bases derived from 1-alkylisatin and isonicotinic acid hydrazide (INH).

N'-(1-alkyl-2,3-dihydro-2-oxo-1H-3-indolyliden)-4-pyridinecarboxylic acid hydrazide derivatives, 3(a-g), were synthesized in a trial to overcome the resistance developed with the therapeutic uses of isoniazid (INH). The lipophilicity of the synthesized derivatives supersedes that of the INH as expressed by Clog p values. The synthesized compounds and INH were tested against bovin, human sensiti...

Isonicotinic acid hydrazide (rimifon) in the treatment of tuberculosis.

Following reports on the effectiveness of isonicotinic acid hydrazide in the treatment of tuberculosis,’ a clinical trial was instituted at the San Angel Sanatorium in Mexico City. Beginning in March 1952, a series of 13 hospitalized and 12 ambulatory patients were started on therapy with Rlmifon* and the results evaluated at the end of a 90-day period. The hospitalized patients selected for st...